HPV16 E7 Rabbit Polyclonal Antibody

SKU: orb10573

Description

HPV16 E7 Rabbit Polyclonal Antibody

Research Area

HPV, Infectious Disease, Human Papillomavirus, Infectious Disease

Images & Validation

• Tested Applications: FC, IF, IHC-Fr, IHC-P, WB
• Dilution Range: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1ug/Test
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from HPV16 E7 protein (41-90/98aa)
• Target: L2
• Molecular Weight: 11 kDa
• Purification: affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

E7; HPV16 E7 protein; HPV 16 E7 protein; Human Papilloma Virus; Human papillomavirus type 16 E7; Human papillomavirus type 16 E7; Protein E7; Human Papillomavirus 16(E7); HPV16 E7; E7 protein(HPV16); VE7_HPV16; HPV16-E7.

Quick Database Links

Gene Symbol

L2

Hu, Zheng et al. TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy J Clin Invest, 125, 425-436 (2015)

PubMed: 25500889

Applications

IHC, WB

Reactivity

Mouse

Gao, Chun et al. The application of CRISPR/Cas9 system in cervical carcinogenesis Cancer Gene Ther, (2021)

PubMed: 34349239

Applications

IF, IHC, WB

Reactivity

Mouse

Xiong, Jinfeng et al. E7-Targeted Nanotherapeutics for Key HPV Afflicted Cervical Lesions by Employing CRISPR/Cas9 and Poly (Beta-Amino Ester) Int J Nanomedicine, 16, 7609-7622 (2021)

PubMed: 34819726

Applications

IHC

Reactivity

Mouse

Zhu, Da et al. Nanoparticles Based on Poly (β-Amino Ester) and HPV16-Targeting CRISPR/shRNA as Potential Drugs for HPV16-Related Cervical Malignancy Mol. Ther., 26, 2443-2455 (2018)

PubMed: 30241742

Applications

IF, IHC

Reactivity

Mouse

Li, Mengtao et al. Exposure to microbial metabolite butyrate prolongs the survival time and changes the growth pattern of HPV16 E6/E7-immortalized keratinocytes in vivo Am J Pathol, (2021)

PubMed: 34214507

Applications

IF

Reactivity

Mouse

Zheng Feng , Zhouzhan Luo Therapeutic efficacy of CRISPR RNA nanoparticles on cervical cancer disease using ultrasound elastography imaging Journal of Radiation Research and Applied Sciences, (2024)

PubMed: