CBL0137 hydrochloride

SKU: orb2704075

Description

CBL0137 (CBL-0137) activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex).

Key Properties

• CAS Number: [1197397-89-9]
• MW: 372.89
• Formula: C₂₁H₂₅CLN₂O₂
• SMILES: CC(C1C=C2C(N(CCNC(C)C)C3=CC=C(C=C32)C(C)=O)=CC=1)=O.Cl

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only