DC-Chol

SKU: orb1910147

Description

DC-Chol is a cationic cholesterol derivative. DC-Chol, as a component of lipoplexes with DOPE, has been used for transfection of mRNA into A549 cells without affecting cell viability. Incubation of DC-chol/DOPE liposomes or lipoplexes with human whole blood has no effect on neutrophil elastase or β-thromboglobulin levels or the number of platelets and red and white blood cells, indicating hemocompatibility. DC-Chol has also been widely used in the synthesis of liposomes for the delivery of siRNA, DNA, and chemotherapeutic agents into cells and mice.

Key Properties

• CAS Number: [166023-21-8]
• MW: 537.26018
• Formula: C₃₂H₅₆N₂O₂.HCL
• SMILES: Cl.CN(CCNC(OC1CCC2(C3CCC4(C(CCC4C3CC=C2C1)C(CCCC(C)C)C)C)C)=O)C

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only