Human IL-9 protein

SKU: orb107753

Description

Interleukin-9 (IL-9) is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells. IL-9 wasoriginally identified as a cytokine found in the conditioned medium of a human T cell leukemia virus type I (HTLVI)transformed T cell line. It functions through the IL-9 receptor, which activates different signal transducer and activator (STAT)proteins and thus connects this cytokine to various biological processes. IL-9 can support the growth of IL-2 independent and IL-4 independent helper T-cells. Human IL-9 has approximately 56 % amino acid sequence identity with murine IL-9. The geneencoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthmademonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: IL-9
• Conjugation: Unconjugated
• MW: 14.1 kDa
• Purity: > 95 % by SDS-PAGE and HPLC analyses
• Protein Sequence: QGCPTLAGIL DINFLINKMQ EDPASKCHCS ANVTSCLCLG IPSDNCTRPC FSERLSQMTNTTMQTRYPLI FSRVKKSVEV LKNNKCPYFS CEQPCNQTTA GNALTFLKSL LEIFQKEKMRGMRGKI

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 m filtered concentrated solution in PBS, pH 7.4.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Human Interleukin-9 protein

Quick Database Links

Gene Symbol

IL-9