Piccolo Antibody: APC

SKU: orb152167

Description

Rabbit polyclonal to Picollo (APC). Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1..

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Neuroscience,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Neuroscience | Cell Markers | Neuron Markers | Presynaptic Markers

Images & Validation

• Tested Applications: ICC, IF, IHC
• Dilution Range: WB (1:1000), IHC (1:400)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml of SPC-197 was sufficient for detection of Piccolo in 10 µg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant Full length Protein, BC001304.1
• Target: Piccolo
• Molecular Weight: 550kDa
• Conjugation: APC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ACZ antibody, Aczonin antibody, Brain-derived HLMN protein antibody, DKFZp779G1236 antibody, KIAA0559 antibody, Multidomain presynaptic cytomatrix protein antibody, PCLO antibody, PCLO_HUMAN antibody, Piccolo (presynaptic cytomatrix protein) antibody, Piccolo mouse homolog of Pico antibody, Presynaptic cytomatrix protein antibody, Protein piccolo antibody

Quick Database Links

Gene Symbol

Piccolo

UniProt

Q9Y6V0

NCBI Gene ID

27445

RefSeq (Protein):NP_055325.2