Randox - Monocyte Chemotactic Protein-1 (MCP-1)

SKU: RCP9095

Description

MCP-1 is a member of the CC subgroup of the chemokine superfamily. It is produced by a variety of cell types including monocytes, lymphocytes, endothelial cells and fibroblasts after stimulation by any inflammatory mediator. MCP-1 acts as a potent chemoattractant and is thought to play an important role in the inflammatory response of blood monocytes, tissue macrophages and natural killer cells. Its expression has been documented in disorders characterized by mononuclear cell infiltrates, suggesting that it may contribute to the inflammatory component of diseases such as atherosclerosis, multiple sclerosis, or rheumatoid arthritis.

Research Area

,For R&D Purposes

Images & Validation

• Application Notes:
  ELISA, Western Blotting, etc.

Key Properties

• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Tag: N terminal containing a HIS tag
• Protein Length: Gln24-Thr99
• MW: 13.19 kDa
• Purity: > 95 %, by SDS-PAGE under reducing conditions

Storage & Handling

• Storage: at -20 °C
• Form/Appearance: Liquid
• Buffer/Preservatives: 20 mM Tris-HCl pH 8.0, 50% Glycerol
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Monocyte chemotactic protein 1; Chemokine (C-C motif) ligand 2 (CCL2); Monocyte chemoattractant protein-1; Monocyte cemotactic and activating factor (MCAF); Monocyte secretory protein JE; small inducible cytokine A2; Small inducible cytokine subfamily A member 2; HC11; SCYA2; SMC-CF; GDCF-2; MGC9434.

Quick Database Links

UniProt

P13500