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Ruxolitinib (INCB018424)

SKU: orb180800

Description

Ruxolitinib is a potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5 nM, respectively and is relatively less selective for JAK3 (IC50 = 322 nM).

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Images & Validation

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Key Properties

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CAS Number[941678-49-5]
MW306.37
FormulaC17H18N6
SMILESC1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3

Storage & Handling

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Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Available Sizes

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1 ml x 10 mm (in DMSO)
$ 300.00
100 mg
$ 490.00
250 mg
$ 890.00
1 g
$ 1,670.00
DispatchUsually dispatched within 5-10 working days
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