SB 203580 hydrochloride

SKU: orb1909166

Description

SB 203580 hydrochloride (Adezmapimod hydrochloride) is a selective, ATP-competitive p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy and inhibits SAPK2a/p38, SAPK2b/p38β2, LCK, GSK3β, and PKBα. SB 203580 hydrochloride has been shown to be useful in antiretroviral therapy. 203580 hydrochloride inhibits amphoteric mechanical anomalous pain in a mouse model of antiretroviral-induced neuropathic pain.

Research Area

,Angiogenesis|||MAPK|||Tyrosine Kinase/Adaptors

Key Properties

• CAS Number: 869185-85-3
• MW: 413.9
• Purity: 98.00%
• Formula: C₂₁H₁₇ClFN₃OS
• SMILES: Cl.O=S(C=1C=CC(=CC1)C2=NC(C=3C=CN=CC3)=C(N2)C=4C=CC(F)=CC4)C

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16760644