Triton X-100

SKU: orb1745264

Description

Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is listed as an excipient in certain vaccines including split virus influenza vaccines. Triton X-100 is a nonionic surfactant [1] [2].

Research Area

,Others

Key Properties

• CAS Number: 9002-93-1
• MW: 208.26
• Purity: 98.00%
• Formula: C₁₄H₁₂N₂
• SMILES: N.CC(C)(C)CC(C)(C)c1ccc(OCCO)cc1

Bioactivity

• In Vitro:
  Triton X-100 (ranging from 0.5% to 0.05%; 1 h; Vero E6 cells) obtained with WNV showed that infectivity was reduced by 6 Logs. This effect was not time-dependent using 0.1% Triton X-100. We applied the method to EBOV and one-hour exposure to 0.1% Triton X-100 strongly affected EBOV infectivity (4 Logs of infectivity reduction).
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162678886