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8-Oxo-dGTP
SKU: orb64224
Description
Images & Validation
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Item 1 of 2
| Application Notes |
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Key Properties
−| CAS Number | 139307-94-1 |
|---|---|
| MW | Theoretical MW: 523.18 g/mol (free acid); Detected MW: 522.99 g/mol (free acid) |
| Purity | ≥ 95% (HPLC) |
| Formula | C10H16N5O14P3 |
| SMILES | Nc1[nH]c(=O)c2c(n(c(=O)[nH]2)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)C2)n1 |
Customer Validated Data
− The data below is submitted by researchers worldwide. We provide this transparency to help you decide if this product works for your specific application or species, even if we haven't tested it ourselves.
Success by Application
Reactivity Distribution
Latest Experiments
6 ResultsDilution
Sample
Summary
Mutagenesis
Escherichia coli, yeast
1.5 μM
Plasmid DNA or PCR-amplified gene fragments
8-Oxo-dGTP is primarily used as a...
DNA repair fidelity analysis
Mouse
200 μM
Synthetic DNA substrates and mouse embryonic fibroblast (MEF) cells
8-Oxo-dGTP is used as an oxidized...
Enzyme activity / nucleotide sanitization assays
Rice (Oryza sativa)
0.1 mM
Purified OsNUDX2 protein and in vitro reaction mixtures
8-Oxo-dGTP is used as an oxidized...
Oxidized nucleotide quantification (LC-MS/MS)
Human
10 mM
Cell pellets, intracellular nucleotide extracts, and isolated total/small RNA derived from cultured cells.
8-Oxo-dGTP is used as an oxidized...
Enzyme activity / nucleotide sanitization assays
Human
-
Cultured cells, cell lysates, and purified recombinant proteins (MTH1 enzyme)
8-Oxo-dGTP is used as an oxidized...
Previous
Storage & Handling
−| Storage | store at -20 °C |
|---|---|
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
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Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].
Compound Identifiers
PubChem CID
Key Properties
− No computed properties available.
Protocol Information
Xiangxiang Wang, Yuyu Zhao, Zhaohua Hou, Xiaoxu Chen, Shuangying Jiang, Wei Liu, Xin Hu, Junbiao Dai, Guangh Large-scale pathway reconstruction and colorimetric screening accelerate cellular metabolism engineering Metabolic Engineering, 80, 107-118 (2023)
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