9-keto Fluprostenol isopropyl ester

SKU: orb2283583

Description

9-Keto Fluprostenol Isopropyl Ester, an ester derivative of the FP receptor agonist fluprostenol, undergoes oxidation at carbon 9. This compound serves as a potential prodrug for 9-keto fluprostenol, which may function as an agonist at EP receptors. Additionally, it is considered a possible metabolite of fluprostenol isopropyl ester (travoprost), drawing parallels to the metabolism of latanoprost by 15-hydroxyprostaglandin dehydrogenase observed in monkey cornea. Furthermore, certain F-series prostaglandins, such as 6-keto prostaglandin F1α (PGF1α), undergo conversion to their E-series counterparts in isolated human platelets, highlighting a metabolic pathway of relevance.

Research Area

,Others

Key Properties

• CAS Number: 1219032-18-4
• MW: 498.5
• Purity: 98.00%
• Formula: C₂₆H₃₃F₃O₆
• SMILES: C(/C=C\CCCC(OC(C)C)=O)[C@@H]1[C@@H](/C=C/[C@H](COC2=CC(C(F)(F)F)=CC=C2)O)[C@H](O)CC1=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

45139170