ABT-263 (Navitoclax)

SKU: orb180801

Description

ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Research Area,Signaling Pathways,Product Categories/Products/Small Molecules/Inhibitors,Signaling Pathways/Apoptotic

Key Properties

• CAS Number: [923564-51-6]
• MW: 974.61
• Formula: C₄₇H₅₅ClF₃N₅O₆S₃
• SMILES: ClC1C([H])=C([H])C(=C([H])C=1[H])C1C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C=1C([H])([H])N1C([H])([H])C([H])([H])N(C2C([H])=C([H])C(C(N([H])S(C3C([H])=C([H])C(=C(C=3[H])S(C(F)(F)F)(=O)=O)N([H])[C@@]([H])(C([H])([H])SC3C([H])=C([H

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of ABT-263 (Navitoclax)