AEE-788 (NVP-AEE788)

SKU: orb154724

Description

AEE788 is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1. Phase 1/2.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [497839-62-0]
• MW: 440.58
• Formula: C₂₇H₃₂N₆
• SMILES: C[C@H](C1=CC=CC=C1)NC2=C(C=C3C(C=C4)=CC=C4CN5CCN(CC)CC5)C(N3)=NC=N2

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of AEE-788 (NVP-AEE788)