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Afatinib (BIBW2992)

SKU: orb154707

Description

BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Images & Validation

Key Properties

CAS Number[439081-18-2]
MW485.9384
FormulaC24H25N5O3FCL
SMILESCN(C)C\C=C\C(=O)NC1=C(OC2COCC2)C=C3C(=C1)C(=NC=N3)NC4C=C(Cl)C(F)=CC=4

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Afatinib (BIBW2992)

Chemical structure of Afatinib (BIBW2992)

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Afatinib (BIBW2992) (orb154707)

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Available Sizes

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1 ml x 10 mm (in DMSO)
$ 300.00
100 mg
$ 360.00
250 mg
$ 620.00
1 g
$ 1,150.00
DispatchUsually dispatched within 5-10 working days.
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