AMG-47a

SKU: orb180770

Description

AMG-47a is a potent inhibitor of Lck and T cell proliferation; exhibits anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [882663-88-9]
• MW: 535.5601
• Formula: C₂₉H₂₈F₃N₅O₂
• SMILES: FC(C1C([H])=C([H])C([H])=C(C=1[H])N([H])C(C1C([H])=C([H])C(C([H])([H])[H])=C(C=1[H])C1C([H])=C([H])C2C(=C([H])N=C(N=2)N([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C=1[H])=O)(F)F

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of AMG-47a