AMG517

SKU: orb180918

Description

AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Small Molecules/Agonists and Antagonists,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [659730-32-2]
• MW: 430.403
• Formula: C₂₀H₁₃F₃N₄O₂S
• SMILES: S1C(N([H])C(C([H])([H])[H])=O)=NC2=C(C([H])=C([H])C([H])=C12)OC1C([H])=C(C2C([H])=C([H])C(C(F)(F)F)=C([H])C=2[H])N=C([H])N=1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of AMG517