Anti-CD166(praluzatamab biosimilar) mAb

SKU: orb1826916

Description

Anti-CD166(praluzatamab biosimilar) mAb

Research Area

,Biosimilar reference antibodies

Images & Validation

• Tested Applications: FC
• Dilution Range: Flow Cyt 1:100
• Reactivity: Human
• Application Notes:
  Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Key Properties

• Antibody Type: Biosimilar Antibody
• Host: Human Humanized
• Clonality: Monoclonal
• Isotype: IgG1
• Target: CD166
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ALCAM;MEMD

CD166 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with 15 μg/mL Anti-CD166 (praluzatamab biosimilar) mAb (orb1826916) on Expi293 cells transfected with Human CD166 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

Flow cytometry analysis of antigen binding of anti-human CD166 mAb (orb1826916). (A) orb1826916 does not bind to K562 cells that do not express CD166. (B) A clear peak shift of orb1826916 was seen compared to the control when incubated with CD166-expressing Hela cells, indicating strong binding of orb1826916 to CD166. Antibodies were incubated at 5 μg/mL.

Flow cytometry analysis of antigen binding of anti-human CD166 mAb (orb1826916). (A) orb1826916 does not bind to K562 cells that do not express CD166. (B) A clear peak shift of orb1826916 was seen compared to the control when incubated with CD166-expressing Huh7 cells, indicating strong binding of orb1826916 to CD166. Antibodies were incubated at 5 μg/mL.

Quick Database Links

Gene Symbol

CD166

UniProt

Q13740