Anti-CSF1R(cabiralizumab biosimilar) mAb

SKU: orb1173645

Description

Anti-CSF1R(cabiralizumab biosimilar) mAb

Research Area

Product Categories/Products/Antibodies,Biosimilar reference antibodies

Images & Validation

• Tested Applications: ELISA, FC
• Dilution Range: ELISA 1:5000-10000|Flow Cyt 1:100
• Reactivity: Human
• Application Notes:
  Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Key Properties

• Antibody Type: Biosimilar Antibody
• Host: Human Humanized
• Clonality: Monoclonal
• Isotype: IgG4
• Target: CSF1R
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Powder
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CSF1R;C-FMS;CD115;CSFR;FIM2;FMS;M-CSFR

ELISA plate pre-coated by 1 μg/ml (100 μL/well) Human CSF1R, His tagged protein orb689415 can bind Anti-CSF1R Neutralizing antibody (orb1173645) in a linear range of 0.2-16 ng/ml.

Flow cytometry analysis with Anti-CSF1R mAb 1 μg/ml (cabiralizumab) on Expi293 cells transfected with human CSF1R (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Flow cytometry analysis of antigen binding of anti-human CSF1R mAb (orb1173645). (A) A clear peak shift of orb1173645 was seen compared to the control when incubated with CSF1R-expressing THP-1 cells, indicating strong binding of orb1173645 to CSF1R. Antibodies were incubated at 2 μg/mL.

Quick Database Links

Gene Symbol

CSF1R

UniProt

P07333