Anti-EGFR Antibody

SKU: orb304743

Description

Rabbit polyclonal antibody to EGFR which is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII.

Research Area

Infectious Diseases,Product Categories/Research Area,Product Categories/Antibodies,Epigenetics,Product Categories/Products/Antibodies/Primary Antibodies,Developmental Biology,Product Categories/Products/Antibodies,Cancer

Images & Validation

• Tested Applications: IF, IH, WB
• Dilution Range: WB: 1:500-1000, IHC-P: 1:100-200, IF/ICC: 1:100-500
• Reactivity: Human, Mouse, Porcine, Rat, Zebrafish

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human EGFR. The exact sequence is proprietary.
• Target: EGFR
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-ERBB antibody, anti-ERBB1 antibody, anti-HER1 antibody, anti-Epidermal growth factor receptor antibody, anti-Proto-oncogene c-ErbB-1 antibody, anti-Receptor tyrosine-protein kinase erbB-1 antibody

Quick Database Links

Gene Symbol

EGFR

UniProt

Q01279, P00533

NCBI Gene ID

1956, 13649