Anti-EGFR [C225 (Cetuximab)]

SKU: orb348862

Description

Human monoclonal antibody to EGFR

Research Area

Infectious Diseases,Product Categories/Products/Antibodies,Developmental Biology,Product Categories/Research Area,Epigenetics,Product Categories/Antibodies,Cancer,tumor marker; biosimilar

Images & Validation

• Tested Applications: Blocking, FC
• Reactivity: Human

Key Properties

• Host: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: C225 (Cetuximab)
• Immunogen: The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
• Target: EGFR
• Purity: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EGFR, ErbB-1, HER1; epidermal growth factor receptor

Quick Database Links

Gene Symbol

EGFR

UniProt

P00533

Prewett, M. et al. The biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinoma J Immunother Emphasis Tumor Immunol, 19, 419-427 (1996)

PubMed: 9041461

Reactivity

Human