Anti-GPR41 Antibody

SKU: orb214002

Description

Rabbit polyclonal antibody to FFAR3 also known as G-protein coupled receptor41 whose expression can be detected in the sympathetic ganglia and is highly expressive in the adipose tissues. It is found in the cell membrane. This protein controls the production of hormones involved in whole-body energy homeostasis, for instance it regulates blood pressure through renin secretion and may also regulate secretion of the PYY peptide by enteroendocrine cells and controls gut motility, intestinal transit rate, and the harvesting of energy from SCFAs produced by gut microbiota. It can also mediate the activation of the inflammatory and immune response by SCFAs in the gut regulating the rapid production of chemokines and cytokines by intestinal epithelial cells.

Research Area

Immunology,Product Categories/Research Area,Signaling Pathways/GPCR,Product Categories/Antibodies,Neuroscience,Signaling Pathways,Epigenetics,Product Categories/Products/Antibodies/Primary Antibodies,Product Categories/Products/Antibodies

Images & Validation

• Tested Applications: IF, WB
• Dilution Range: WB: 1-500-1-1000
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GPR41. The exact sequence is proprietary.
• Target: FFAR3
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-GPR41 antibody, anti-Free fatty acid receptor 3 antibody, anti-G-protein coupled receptor 41 antibody

Quick Database Links

Gene Symbol

FFAR3

UniProt

Q3UFD7, O14843

NCBI Gene ID

233080, 2865