Anti-GPx-4 Antibody

SKU: orb340797

Description

Rabbit polyclonal antibody to GPX4

Research Area

Product Categories/Research Area,Product Categories/Antibodies,Epigenetics,Product Categories/Products/Antibodies/Primary Antibodies,Developmental Biology,Product Categories/Products/Antibodies

Images & Validation

• Tested Applications: IF, IH, WB
• Dilution Range: WB: 1:500-1:2000, IHC-P: 1:50-1:200, IF/ICC: 1:10-1:100
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant full length protein of human GPx-4
• Target: GPX4
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Phospholipid hydroperoxide glutathione peroxidase mitochondrial; PHGPx; Glutathione peroxidase 4; GPx-4; GSHPx-4

Quick Database Links

Gene Symbol

GPX4

UniProt

P36969

NCBI Gene ID

2879

G Tian, J Li, W Wang, L Zhou FGF12 restrains mitochondria‐dependent ferroptosis in doxorubicin‐induced cardiomyocytes through the activation of FGFR1/AMPK/NRF2 signaling Drug Development Research, (2024)

PubMed:

Applications

WB

Reactivity

Mouse

Xiaoshan Chen 1, Wei Wang 2, Wei Wei TRIM22 mechanism promoting KAT2A ubiquitination degradation to regulate ferroptosis in hepatocellular carcinoma cell invasion and metastasis Histol Histopathol ., (2024)

PubMed: 39698827

F Ye, Y Xu, X Zhu, Q Ding, Y Wang, S Lu, Y Chen The mechanism of E3 ubiquitin ligase HERC1 regulating ferroptosis in lung adenocarcinoma cells Cancer Genetics, (2025)

PubMed:

Applications

WB

Reactivity

Human

Li, Meng et al. Melatonin Inhibits the Ferroptosis Pathway in Rat Bone Marrow Mesenchymal Stem Cells by Activating the PI3K/AKT/mTOR Signaling Axis to Attenuate Steroid-Induced Osteoporosis Oxid Med Cell Longev, 2022, 8223737 (2022)

PubMed: 36035224

Ma, Xiaojun et al. Lidocaine attenuates hypoxia/reoxygenation?induced inflammation, apoptosis and ferroptosis in lung epithelial cells by regulating the p38 MAPK pathway Mol Med Rep, 25, 150 (2022)

PubMed: 35244190