Anti-LYN (Phospho-Y397) Antibody

SKU: orb315590

Description

Rabbit polyclonal antibody to LYN (Phospho-Y397) also known as p53Lyn and p56Lyn whose expression can be detected in the placenta and fetal brain but is highly expressive in the neuroblastoma tumors and neuronal cells. It is found in the perinuclear region. This protein is a Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents.

Research Area

Infectious Diseases,Immunology,Product Categories/Research Area,Product Categories/Antibodies,Epigenetics,Product Categories/Products/Antibodies/Primary Antibodies,Product Categories/Products/Antibodies,Cancer

Images & Validation

• Tested Applications: IF, IH, WB
• Dilution Range: WB: 1-500:1000, IHC-P: 1-100:200, IF/ICC: 1-100:500
• Reactivity: Human, Mouse, Porcine, Rat, Sheep

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y397 of human LYN protein. The exact sequence is proprietary.
• Target: LYN
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-JTK8 antibody, anti-Tyrosine-protein kinase Lyn antibody, anti-Lck/Yes-related novel protein tyrosine kinase antibody, anti-V-yes-1 Yamaguchi sarcoma viral related oncogene homolog antibody, anti-p53Lyn antibody, anti-p56Lyn antibody

Quick Database Links

Gene Symbol

LYN

UniProt

P07948, Q07014, P25911

NCBI Gene ID

81515, 4067, 17096