Anti-MASP2 Reference Antibody (narsoplimab)

SKU: orb1818291

Description

Recombinant Antibody

Images & Validation

• Tested Applications: ELISA, FC
• Reactivity: Human, Monkey, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: IgG4
• Source/Expression System: CHO Cell
• Protein Sequence: MASP2
• Molecular Weight: 143.1
• Endotoxin: < 0.001EU/μg,determined by LAL method.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mannan-binding lectin serine protease 2, 3.4.21.104, MBL-associated serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2, Mannan-binding lectin serine protease 2 A chain, Mannan-binding lectin serine protease 2 B chain, MASP2

The purity of Anti-MASP2 Reference Antibody (narsoplimab) is more than 98.94%, determined by SEC-HPLC.

Immobilized human MASP 2A His at 2 µg/mL can bind Anti-MASP2 Reference Antibody (narsoplimab), EC50=0.006278 µg/mL

C5b-C9 of the MBL pathway can be completely inhibited by Anti-MASP2 Reference Antibody (narsoplimab) with an IC50 of 0.7337 µg/mL.

Anti-MASP2 Reference Antibody (narsoplimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%

Quick Database Links

UniProt

O00187