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Antibiofilm agent-12

SKU: orb2664856

Description

Antibiofilm agent-12 (Compound C13), an antifungal belonging to the carbamate derivatives, exhibits significant antifungal activity against Candida auris, with an MIC90 of 237.9 μM. It inhibits the drug efflux pump activity of Candida auris and promotes ergosterol depletion, thereby hindering the formation of Candida auris biofilms and reducing its metabolic flexibility. Additionally, Antibiofilm agent-12 demonstrates antifungal efficacy in a C. elegans model following Candida auris infection.

Images & Validation

Key Properties

CAS Number480452-24-2
MW262.69
Purity98.00%
FormulaC13H11ClN2O2
SMILESO=C(OC=1C=CC=CC1)NNC2=CC=C(Cl)C=C2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information