AS-8351

SKU: orb1713548

Description

KDM5B histone demethylase inhibitor

Key Properties

• CAS Number: 796-42-9
• MW: 291.3
• Purity: > 98% (TLC); NMR (Conforms)
• Formula: C₁₇H₁₃N₃O₂
• SMILES: O=C(NN\C=C1/C(=O)C=Cc2ccccc12)c3ccncc3
• Solubility: May be dissolved in DMSO (45 mg/ml); or ethanol (10 mg/ml, warm); or DMF (30 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Hazard Information: GHS Classification: Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Signal word: Warning Hazard statement(s): H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statement(s): P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.
• Disclaimer: For research use only

Alternative Names

AS8351, 2-Hydroxy-1-naphthylaldehyde isonicotinoylhydrazone; NSC-51355, N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide, N'-[(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide, N'-[(Z)-(2-oxo-1-naphthylidene)methyl]pyridine-4-carbohydrazide, N'-[(2-oxo-1-naphthylidene)methyl]pyridine-4-carbohydrazide, N'-[(Z)-(2-oxo-1-naphthylidene)methyl]-4-pyridinecarbohydrazide, N'-[(2-oxo-1-naphthylidene)methyl]-4-pyridinecarbohydrazide, N'-[(Z)-(2-keto-1-naphthylidene)methyl]isonicotinohydrazide, N'-[(2-keto-1-naphthylidene)methyl]isonicotinohydrazide, 796-42-9, 2-Hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone, NSC51355, NCI60_004242, ZINC00061171, CBDivE_006818, 311 Iron Chelator, 2-Hydroxy-1-naphthaldehyde isonicotinoyl hydrazone

Chemical structure of AS-8351, a KDM5B histone demethylase inhibitor. CAS #: 796-42-9. Molecular Formula: C17H13N3O2. Molecular Weight: 291.3 g/mol.