ASK1 (MEKK5/MAP3K5) Antibody (S966)

SKU: orb38714

Description

Rabbit polyclonal antibody to ASK-1 (apoptosis signal-regulating kinase 1 - also referred to as MEK Kinase-5 or MAPKKK5), belongs to the protein kinase superfamily, MAP kinase kinase kinase subfamily. It is playing a central role in DNA replication and cell proliferation and also involved in regulating the initiation of DNA replication during cell cycle. It is required for progression of S phase. ASK-1 is expressed in a variety of human and mouse tissues.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cancer,Cardiovascular Disease,Neuroscience,Signaling Pathways,Signaling Pathways/Apoptotic,Immunology,Epigenetics,Infectious Diseases,Primary Antibodies;Antibody Collections;Cardiovascular;Cell Biology;Amyotrophic Lateral Sclerosis (ALS);Viral process;Host-virus interaction;Immunity;Innate immunity;Apoptosis signaling;Stress response

Images & Validation

• Tested Applications: WB
• Dilution Range: WB: 1:1000
• Reactivity: Human
• Predicted Reactivity: Mouse

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB12750
• Immunogen: Synthetic Peptide
• Target: MAP3K5
• Molecular Weight: 154537
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-Mitogen-activated protein kinase kinase kinase 5 antibody, anti-MAPK/ERK kinase kinase 5 antibody, anti-MEK kinase 5 antibody, anti-MEKK 5 antibody, anti-Apoptosis signal-regulating kinase 1 antibody, anti-ASK-1 antibody, anti-MAP3K5 antibody

Quick Database Links

Gene Symbol

MAP3K5

UniProt

Q99683

RefSeq (Protein):NP_005914.1