AT-406

SKU: orb181200

Description

AT-406 (formerly known as SM-406) is an orally bioavailable potent IAP (inhibitor of apoptosis protein) of XIAP, cIAP1, and cIAP2 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, respectively.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Research Area,Signaling Pathways,Product Categories/Small Molecules/Agonists and Antagonists,Product Categories/Products/Small Molecules/Inhibitors,Signaling Pathways/Apoptotic

Key Properties

• CAS Number: [1071992-57-8]
• MW: 597.31
• Formula: C₃₂H₄₃N₅O₄
• SMILES: O=C1[C@H](CN(C(CC(C)C)=O)CC[C@H]2CC[C@@H](C(NC(C3C=CC=CC=3)C3C=CC=CC=3)=O)N21)NC([C@H](C)NC)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of AT-406