[Au(L4)(CyJohnPhos)]SbF6

SKU: orb2695448

Description

[Au(L4)(CyJohnPhos)]SbF6 is a gold-containing compound that exhibits inhibitory effects on cyclooxygenase-1/2 (COX-1/2), suppresses the proliferation of colon cancer cells Caco2-/TC7 with an IC50 of 0.98 μM, and induces cell apoptosis (apoptosis). Additionally, [Au(L4)(CyJohnPhos)]SbF6 acts as an inhibitor of thioredoxin reductase (TrxR) and demonstrates antioxidative activity by modulating ROS levels.

Research Area

,NF-κB|||Neuroscience|||Apoptosis|||Immunology/Inflammation|||Metabolism

Key Properties

• MW: 1158.68
• Formula: C₄₄H₅₆AuF₆NO₄PSSb

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only