AZD1080

SKU: orb146240

Description

AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows > 14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [612487-72-6]
• MW: 334.3718
• Formula: C₁₉H₁₈N₄O₂
• SMILES: O1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C(C([H])=C2[H])C2=C(N([H])C3C([H])=C([H])C(C#N)=C([H])C2=3)O[H])C([H])([H])C1([H])[H]

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of AZD1080