Azd1897

SKU: orb2702891

Description

AZD1897 is a PIM1, PIM2, and PIM3 inhibitor with IC50 values of less than 3 nM for these three PIM kinases. AZD1897 exhibits anticancer activity and synergistically inhibits the activity of acute myeloid leukemia (AML) cells in combination with Capivasertib (HY-15431). This synergistic inhibitory effect is achieved through the inhibition of the mTOR and MCL1 pathways.

Key Properties

• CAS Number: [1204181-93-0]
• MW: 361.46
• Formula: C₁₈H₂₃N₃O₃S
• SMILES: O=C(NC/1=O)SC1=C/C2=CC=CC(OC(C)C)=C2N3C[C@H](N)CCC3

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only