Baricitinib (INCB28050, LY3009104)

SKU: orb146247

Description

Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2,showed potent activity against COVID-19(SARS-COV-2).

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [1187594-09-7]
• MW: 371.417
• Formula: C₁₆H₁₇N₇O₂S
• SMILES: N(S(CC)(=O)=O)1CC(N2C=C(C3N=CN=C4NC=CC4=3)C=N2)(CC#N)C1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only