BATF3 Antibody / SNFT

SKU: orb1824173

Description

SNFT, also known as BATF3 (basic leucine zipper transcription factor, ATF-like 3), JUNDM1 or JDP1, is a 127 amino acid protein that localizes to the nucleus and contains one bZIP domain. Interacting with c-Jun, SNFT functions as a negative regulator of AP-1-mediated transcription, specifically by heterodimerizing with c-Jun and binding to DNA response elements. The gene encoding SNFT maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Images & Validation

• Tested Applications: FACS, IHC-P
• Dilution Range: Flow cytometry: 1-2ug/million cells,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1, kappa
• Clone No.: PCRP-BATF3-1E5
• Immunogen: A recombinant partial protein sequence (within amino acids 1-123) from the human protein was used as the immunogen for the SNFT antibody.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Aliquot the SNFT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Hazard Information: This SNFT antibody is available for research use only.
• Disclaimer: For research use only

Quick Database Links

UniProt

Q9NR55