Bcl-2 antibody [N1N2], N-term

SKU: orb1742747

Description

BCL-2 antibody recognizes BCL-2 protein. BCL-2 (26 kDa) regulates mitochondrial dynamics, is involved in the regulation of mitochondrial fusion and fission, and is associated with apoptosis. Abnormal expression of BCL-2 protein is linked to various cancers, autoimmunity, and psychiatric disorders. This BCL-2 antibody is a widely published rabbit polyclonal validated for multiple applications.

Images & Validation

• Tested Applications: ICC, IHC-P, WB
• Dilution Range: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
• Reactivity: Canine, Feline, Human, Mouse, Rat, Zebrafish
• Application Notes:
  Positive control: BCL2-transfected 293T

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Bcl-2. The exact sequence is proprietary.
• Target: BCL2 apoptosis regulator
• Molecular Weight: 26
• Conjugation: Unconjugated

Storage & Handling

• Storage: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.025% ProClin 300. 1XPBS (pH7), 1% rAlbumin, 20% Glycerol
• Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BCL2 apoptosis regulator , Bcl-2 , PPP1R50

Quick Database Links

Gene Symbol

BCL2 apoptosis regulator

UniProt

P10415