Bexarotene

SKU: orb134383

Description

Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 > 10000 nM)[1][2][3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Small Molecules/Agonists and Antagonists

Key Properties

• CAS Number: [153559-49-0]
• MW: 348.4779
• Formula: C₂₄H₂₈O₂
• SMILES: O([H])C(C1C([H])=C([H])C(=C([H])C=1[H])C(=C([H])[H])C1C(C([H])([H])[H])=C([H])C2=C(C=1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of Bexarotene