BIX-01294 trihydrochloride

SKU: orb1306973

Description

Research Area

Product Categories/Products/Small Molecules,Autophagy|||Chromatin/Epigenetic

Images & Validation

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Key Properties

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CAS Number	1392399-03-9
MW	600.02
Purity	99.95%
Formula	C₂₈H₄₁Cl₃N₆O₂
SMILES	Cl.Cl.Cl.COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N1CCCN(C)CC1

Bioactivity

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Target IC50	G9a:2.7 μM
In Vivo	In wild-type embryonic stem (ES) cells, mouse embryonic fibroblasts, and HeLa cells, BIX-01294 (4.1 μM) reduces the levels of H3K9me2. BIX-01294 can specifically inhibit G9a (IC50=1.7 μM) and GLP (IC50=38 μM).

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

46945860 ↗

Key Properties

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No computed properties available.

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