BMS-833923 (XL-139)

SKU: orb180855

Description

BMS 833923 is an orally bioavailable inhibitor of Smo. It blocks binding of BODIPY cyclopamine (IC50 = 21 nM) and inhibits Gli activation in cell lines that express wild-type Smo or activated mutant forms of Smo (IC50s = 6-35 nM). BMS 833923 robustly inhi

Research Area

Product Categories/Products/Small Molecules,Product Categories/Small Molecules/Agonists and Antagonists,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [1059734-66-5]
• MW: 473.57
• Formula: C₃₀H₂₇N₅O
• SMILES: C(NC1=CC(CNC)=CC=C1C)(=O)C1=CC=C(NC2=NC(C3=CC=CC=C3)=C3C(=N2)C=CC=C3)C=C1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of BMS-833923 (XL-139)