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Bromosporine

SKU: orb1300932

Description

Bromosporine

Research Area

Product Categories/Products/Small Molecules,Cell Cycle/Checkpoint|||Chromatin/Epigenetic

Images & Validation

Key Properties

CAS Number1619994-69-2
MW404.44
Purity99.51%
FormulaC17H20N6O4S
SMILESCCOC(=O)Nc1cc(nn2c(C)nnc12)-c1ccc(C)c(NS(C)(=O)=O)c1

Bioactivity

Target IC50
BRD9:0.122 μM|CECR2:0.017 μM|BRD4:0.29 μM|BRD2:0.41 μM
In Vitro
Bromosporine (1 μM) accelerates FRAP recovery of BRD4 and CREBBP, while shows no activities against TIF1α, BAZ2A, and SMARCA2 even at 10 μM. Bromosporine (18 μM) has moderate cytotoxicity in HeLa cells.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Bromosporine (orb1300932)

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Available Sizes

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1 mg
$ 150.00
5 mg
$ 200.00
1 ml x 10 mm (in DMSO)
$ 220.00
10 mg
$ 290.00
25 mg
$ 450.00
50 mg
$ 690.00
100 mg
$ 960.00
500 mg
$ 1,790.00
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