BTdCPU

SKU: orb1568331

Description

BTdCPU is an activator of HRI. The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma. Combination therapy with rapamycin, an mTOR inhibitor, and BTdCPU, an activator of HRI, demonstrated additive effects on apoptosis in dex-resistant cells. Thus, specific activation of the eIF2α kinase HRI is a novel therapeutic target in MM that can augment current treatment strategies.

Research Area

Product Categories/Products/Small Molecules

Key Properties

• CAS Number: [1257423-87-2]
• MW: 339.194
• Formula: C₁₃H₈Cl₂N₄OS
• SMILES: O=C(NC1=CC=C(Cl)C(Cl)=C1)NC2=CC=C3N=NSC3=C2

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only