CD163L1 Antibody

SKU: orb1825814

Description

CD163L1 (CD163 molecule-like 1), also known as scavenger receptor cysteinerich type 1 protein M160 or CD163B, is a 1,453 amino acid protein that belongs to the scavenger receptor cysteine-rich (SRCR) superfamily. Members of the SRCR family contain SRCR domains which are used to influence ligand binding and protein-protein interaction, and are found in cells of the immune system where they exist as membrane-anchored or secreted proteins. Containing 12 SRCR domains, CD163L1 undergoes alternative splicing events to produce 3 isoforms. CD163L1 isoforms 1 and 2 are single-pass type I membrane proteins, unlike isoform 3, which is a secreted protein. CD163L1 isoform 1 is abundantly expressed in lymph node, spleen, thymus and fetal liver, and isoform 2 is found exclusively in spleen. The gene encoding CD163L1 maps to human chromosome 12p13.31.

Images & Validation

• Tested Applications: IHC-P
• Dilution Range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG
• Clone No.: CD163L1/7971
• Immunogen: A recombinant fragment of human CD163L1 protein was used as the immunogen for the CD163L1 antibody.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Aliquot the CD163L1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Hazard Information: This CD163L1 antibody is available for research use only.
• Disclaimer: For research use only

IHC staining of FFPE human lymph node tissue with CD163L1 antibody (clone CD163L1/7971). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

IHC staining of FFPE human spleen tissue with CD163L1 antibody (clone CD163L1/7971). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

IHC staining of FFPE human tonsil tissue with CD163L1 antibody (clone CD163L1/7971). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

SDS-PAGE analysis of purified, BSA-free CD163L1 antibody (clone CD163L1/7971) as confirmation of integrity and purity.

Quick Database Links

UniProt

Q9NR16