CD22 Antibody [hL22 (Epratuzumab)], Rabbit IgG - Research Grade Biosimilar

SKU: orb1671891

Description

CD22 Antibody [hL22 (Epratuzumab)], Rabbit IgG - Research Grade Biosimilar

Research Area

,Cancer,Immunology,Other

Images & Validation

• Tested Applications: Blocking, FC, IP
• Reactivity: Human, Primate

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Recombinant
• Isotype: IgG kappa
• Clone No.: hL22 (Epratuzumab)
• Immunogen: This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5–10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
• Target: CD22
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Concentration: batch dependent
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Leu14, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Sialic acid-binding Ig-like lectin 2, Siglec-2, T-cell surface antigen Leu-14

Flow-cytometry using anti-CD22 antibody Epratuzum28. Human lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Eptratuzum2 - panel B) at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.

Flow-cytometry using anti-CD22 antibody Epratuzum28. Rhesus monkey lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Epratuzum2 - panel B) at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.

Flow-cytometry using anti-CD22 antibody Epratuzum28. Cynomolgus monkey lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Epratuzum2 - panel B at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.

Quick Database Links

Gene Symbol

CD22

UniProt

P20273