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Description
Research Area
Images & Validation
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| Application Notes |
|---|
Key Properties
−| Expression System | HEK293 Cells |
|---|---|
| Biological Origin | Human |
| Biological Activity | The cell surface glycoprotein CD6 is expressed on leukocytes and mediates T cell trafficking across endothelial cell barriers. CD6 is a lymphocyte surface co-receptor physically associated with the T-cell receptor (TCR)/CD3 complex at the center of the immunological synapse. |
| Tag | C-His |
| Expression Region | His18-Leu402 |
| MW | 42.14 kDa (predicted). Due to glycosylation, the protein migrates to 70-90 kDa based on Tris-Bis PAGE result. |
| Purity | 98.00% |
Storage & Handling
−| Storage | -20°C |
|---|---|
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
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The protein has a predicted molecular mass of 41.4 kDa after removal of the signal peptide. The apparent molecular mass of CD6-His is approximately 55-100 kDa due to glycosylation.
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Recombinant Human CD6 Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (His Tag18-Glu398) of human CD6 (Accession #NP_006716.3) fused with an Fc, 6��His Tag at the C-terminus.
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