CD79A Antibody (C-term)

SKU: orb27792

Description

Mouse monoclonal antibody to CD79A is found in the development from the earliest pre-B cell to plasma cells. CD79A is a marker for B-lineage lymphoblastic leukemia. It is required in cooperation with CD79B for initiation of the signal transduction cascade, and is activated by binding of antigen to the B-cell antigen receptor complex (BCR). This leads to internalization of the complex, trafficking to late endosomes and antigen presentation.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cancer,Stem Cells,Immunology,Epigenetics,Primary Antibodies;Cancer;Immunology;Signal Transduction;Immunity;B cell receptor signaling;Immune system process

Images & Validation

• Tested Applications: WB
• Dilution Range: WB: 1:100-250
• Reactivity: Mouse

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone No.: 299CT22.1.2
• Immunogen: Synthetic Peptide
• Target: CD79A
• Molecular Weight: 25038
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-B-cell antigen receptor complex-associated protein alpha chain antibody, anti-CD79A antibody, anti-IGA antibody, anti-MB1 antibody

CD79A Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35 μg/lane). This demonstrates the CD79A antibody detected the CD79A protein (arrow).

Quick Database Links

Gene Symbol

CD79A

UniProt

P11912

RefSeq (Protein):NP_067612.1, NP_001774.1