CDH1 (C2) Antibody, Rabbit Polyclonal

SKU: orb66765

Description

Rabbit polyclonal to CDH1.Cadherin-1 (CDH1) is a single-pass membrane protein. Cadherins are calcium-dependent celladhesion proteins. They preferentially interact with themselves in a homophilic manner in connectingcells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved inmechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. It has a potentinvasive suppressor role. It is a ligand for integrin alpha-E/beta-7. Defects in CDH1 are the cause ofhereditary diffuse gastric cancer (HDGC) and are a cause of susceptibility to endometrial cancer(ENDMC) and ovarian cancer (OC).

Research Area

Product Categories/Products/Antibodies,Epigenetics,Product Categories/Products/Antibodies/Primary Antibodies

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:1000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human CDH1
• Molecular Weight: 97
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-CDH1 antibody,anti-Cadherin1 antibody,anti-CAM 120 antibody,anti-80 antibody,anti-Epithelial cadherin antibody,anti-Ecadherin antibody,anti-Uvomorulin antibody,anti-CD324 antibody,anti-CDHE antibody,anti-UVO antibody

Western blot analysis of total cell extracts from human MCF7(Lane1) and human Hela(Lane2) using CDH1 antibody

Quick Database Links

UniProt

P12830