CDK7-IN-3

SKU: orb1818754

Description

CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity.

Key Properties

• CAS Number: [2417302-07-7]
• MW: 490.46
• Formula: C₂₃H₂₆F₃N₆OP
• SMILES: N#CC1=C(P(C)(C)=O)C2=C(C=C1)C(C3=NC(N[C@@H]4CNC(C)(C)CC4)=NC=C3C(F)(F)F)=CN2

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only