CEBPZ Antibody

SKU: orb1823921

Description

C/EBPZ (CCAAT/enhancer-binding protein Z), also known as CBF, CBF2, NOC1 or HSP-CBF is a 1,054 amino acid nuclear protein belonging to the CBF/MAK21 family. C/EBPZ stimulates transcription from the HSP70 and HSP40 promoters in a NF-Y dependent manner, requiring an intact NF-Y trimer which binds to the DNA. C/EBPZ is thought to be a potential tumor suppressor gene, and aberrant methylation of the C/EBPZ promoter may be involved with acute myeloid leukemia. The C/EBPZ gene is conserved in a wide number of species including chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish and C. elegans and is located on human chromosome 2. Chromosome 2, the second largest human chromosome, consists of 237 million bases encoding over 1,400 genes, comprising approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2.

Images & Validation

• Tested Applications: FACS, IHC-P
• Dilution Range: Flow cytometry: 1-2ug/million cells,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG2c
• Clone No.: PCRP-CEBPZ-2D8
• Immunogen: The protein domain of CEBPZ protein was used as the immunogen for the CEBPZ antibody.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Aliquot the CEBPZ antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Hazard Information: This CEBPZ antibody is available for research use only.
• Disclaimer: For research use only

Quick Database Links

UniProt

Q03701