CEP-32496 hydrochloride

SKU: orb341694

Description

CEP-32496 Hcl is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2.

Research Area

Product Categories/Products/Small Molecules

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Key Properties

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CAS Number	[1227678-26-3]
MW	553.92
Formula	C₂₄H₂₃ClF₃N₅O₅
SMILES	O=C(NC1C=C(OC2N=CN=C3C=C(OC)C(OC)=CC=23)C=CC=1)NC1C=C(C(C(F)(F)F)(C)C)ON=1.[H]Cl

Storage & Handling

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Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Chemical structure of CEP-32496 hydrochloride

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