COL21A1 Protein, Human, Recombinant (His)

SKU: orb1961057

Description

Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interruptedhelices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, oneTSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in manytissues with the highest expression observed at the fetal stage. COL21A1 is stimulated byPDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type Icollagen; it may serve to maintain the integrity of the extracellular matrix.

Research Area

,Recombinant-Protein

Images & Validation

• Application Notes:
  Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Key Properties

• Expression System: HEK293 Cells
• Biological Origin: Human
• Biological Activity: Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I collagen; it may serve to maintain the integrity of the extracellular matrix.
• Tag: C-6xHis
• Expression Region: Glu23-Tyr957
• MW: 115-125&220 KDa (reducing condition)
• Purity: 98.00%
• Protein Sequence: Glu23-Tyr957

Storage & Handling

• Storage: -20°C
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

UniProt

Q96P44