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Description
Research Area
,Recombinant-Protein
Images & Validation
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| Application Notes |
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Key Properties
−| Expression System | Baculovirus Insect Cells |
|---|---|
| Biological Origin | Human |
| Biological Activity | COL4A3BP is a member of the StarD2 subfamily. It contains a pleckstrin homology domain at its amino terminus and a START domain towards the end of the molecule. COL4A3BP has a lipid-binding domain that mediates intracellular trafficking of ceramide in a non-vesicular manner. One isoform of COL4A3BP is also involved in ceramide intracellular transport. COL4A3BP specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. An autoimmune response directed at this antigen can cause goodpasture disease. |
| Tag | His, GST |
| Expression Region | A DNA sequence encoding the human COL4A3BP (Q9Y5P4-1) (Met1-Phe598) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. Predicted N terminal: Met |
| MW | 95.8 kDa (predicted); 96 kDa (reducing conditions) |
| Purity | 98.00% |
Storage & Handling
−| Storage | -20°C |
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| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
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Quick Database Links
UniProt
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Protocol Information
Protein Handling and Storage Guide
Protein Handling Guide
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