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Combretastatin A-1 phosphate tetrasodium

SKU: orb1984509

Description

Combretastatin A-1 phosphate (OXi-4503) tetrasodium, a prodrug of Combretastatin A-1, is a tubulin-binding microtubule polymerization inhibitor targeting the colchicine-binding site. By inducing tubulin depolymerization, it inhibits the Wnt/β-catenin pathway and deactivates AKT, possessing both anti-tumor and anti-vascular properties.

Research Area

,Others

Images & Validation

Key Properties

CAS Number288847-34-7
MW580.24
Purity98.00%
FormulaC18H18Na4O12P2
SMILES[Na].COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)c(OP(O)(O)=O)c1OP(O)(O)=O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information